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VASE

THIS WIKI IS UNDER CONSTRUCTION

What is VASE?

VASE stands for Variant Annotation, Segregation and Exclusion. It provides a program to filter and annotate variant data (in VCF/BCF format) according to user-specified criteria. Example use cases include:

• Annotating/filtering variants on frequency data from public databases (e.g. gnomAD, dbSNP)
• Selecting variants based on VEP consequence annotations
• Filtering variants based on presence in cases vs control samples
• Filtering variants based on familial segregation/inheritance patterns
• Filtering variants/genotypes based on depth data and quality metrics

For installation instructions see the README