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DESCRIPTION
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Type: Package
Package: nlmixr2est
Title: Nonlinear Mixed Effects Models in Population PK/PD, Estimation
Routines
Version: 3.0.2.9000
Authors@R: c(
person("Matthew", "Fidler", , "[email protected]", role = c("aut", "cre"),
comment = c(ORCID = "0000-0001-8538-6691")),
person("Yuan", "Xiong", , "[email protected]", role = "aut"),
person("Rik", "Schoemaker", , "[email protected]", role = "aut",
comment = c(ORCID = "0000-0002-7538-3005")),
person("Justin", "Wilkins", , "[email protected]", role = "aut",
comment = c(ORCID = "0000-0002-7099-9396")),
person("Wenping", "Wang", , "[email protected]", role = "aut"),
person("Robert", "Leary", role = "ctb"),
person("Mason", "McComb", , "[email protected]", role = "ctb",
comment = c(ORCID = "0000-0001-9871-8616")),
person("Vipul", "Mann", , "[email protected]", role = "aut"),
person("Mirjam", "Trame", , "[email protected]", role = "ctb"),
person("Mahmoud", "Abdelwahab", , "[email protected]", role = "ctb"),
person("Teun", "Post", , "[email protected]", role = "ctb"),
person("Richard", "Hooijmaijers", , "[email protected]", role = "aut"),
person("Hadley", "Wickham", role = "ctb"),
person("Dirk", "Eddelbuettel", , "[email protected]", role = "cph"),
person("Johannes", "Pfeifer", role = "ctb"),
person("Robert B.", "Schnabel", role = "ctb"),
person("Elizabeth", "Eskow", role = "ctb"),
person("Emmanuelle", "Comets", , "[email protected]", role = "ctb"),
person("Audrey", "Lavenu", role = "ctb"),
person("Marc", "Lavielle", role = "ctb"),
person("David", "Ardia", role = "cph"),
person("Katharine", "Mullen", role = "cph"),
person("Ben", "Goodrich", role = "ctb")
)
Maintainer: Matthew Fidler <[email protected]>
Description: Fit and compare nonlinear mixed-effects models in
differential equations with flexible dosing information commonly seen
in pharmacokinetics and pharmacodynamics (Almquist, Leander, and
Jirstrand 2015 <doi:10.1007/s10928-015-9409-1>). Differential equation
solving is by compiled C code provided in the 'rxode2' package (Wang,
Hallow, and James 2015 <doi:10.1002/psp4.12052>).
License: GPL (>=3)
URL: https://github.com/nlmixr2/nlmixr2est,
https://nlmixr2.github.io/nlmixr2est/
Depends:
nlmixr2data,
R (>= 4.0)
Imports:
backports,
checkmate,
cli,
graphics,
knitr,
lbfgsb3c,
lotri,
magrittr,
Matrix,
methods,
minqa,
n1qn1 (>= 6.0.1-12),
nlme,
Rcpp,
rex,
rxode2 (>= 3.0.0),
stats,
symengine,
utils
Suggests:
broom.mixed,
crayon,
data.table,
devtools,
digest,
dplyr (>= 1.1.0),
generics,
nloptr,
qs,
sys,
testthat,
tibble,
withr,
xgxr,
sfsmisc,
minpack.lm,
remotes
LinkingTo:
BH,
n1qn1 (>= 6.0.1-12),
lbfgsb3c (>= 2024-3.5),
lotri (>= 0.5.0),
Rcpp,
RcppArmadillo (>= 0.11.2.3.1),
RcppEigen,
rxode2 (>= 3.0.0)
Biarch: true
Config/testthat/edition: 3
Encoding: UTF-8
Language: en-US
NeedsCompilation: yes
RoxygenNote: 7.3.2
LazyData: true