diff --git a/plugins/Karma/plugin.py b/plugins/Karma/plugin.py
index bd896bf30..783575b58 100644
--- a/plugins/Karma/plugin.py
+++ b/plugins/Karma/plugin.py
@@ -272,7 +272,7 @@ def _doKarma(self, irc, msg, channel, thing):
         karma = ''
         for s in inc:
             if thing.endswith(s):
-                thing = thing[:-len(s)]
+                thing = thing[:-len(s)].rstrip(",: ")
                 # Don't reply if the target isn't a nick
                 if onlynicks and thing.lower() not in map(ircutils.toLower,
                         irc.state.channels[channel].users):
@@ -286,7 +286,7 @@ def _doKarma(self, irc, msg, channel, thing):
                 karma = self.db.get(channel, self._normalizeThing(thing))
         for s in dec:
             if thing.endswith(s):
-                thing = thing[:-len(s)]
+                thing = thing[:-len(s)].rstrip(",: ")
                 if onlynicks and thing.lower() not in map(ircutils.toLower,
                         irc.state.channels[channel].users):
                     return
diff --git a/plugins/Karma/test.py b/plugins/Karma/test.py
index 97c178919..f31f168e6 100644
--- a/plugins/Karma/test.py
+++ b/plugins/Karma/test.py
@@ -60,6 +60,10 @@ def testKarma(self):
                           'Karma for [\'"]moo[\'"].*increased 1.*total.*1')
         self.assertRegexp('karma MoO',
                           'Karma for [\'"]MoO[\'"].*increased 1.*total.*1')
+        # Test trailing characters and spaces
+        self.assertNoResponse('baz, ++', 2)
+        self.assertRegexp('karma baz',
+                          'Karma for [\'"]baz[\'"].*increased 1.*total.*1')
 
     def testKarmaRankingDisplayConfigurable(self):
         try: