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reactions.yaml
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- id: 12DAG3Ps_PA
name: 1,2-diacyl-sn-glycerol 3-phosphate synthesis
genes: PA0005 and PA3673
equation: (0.03) ocdACP[c] + (0.51) 2tocdACP[c] + (0.13) hdeACP[c] + (0.5) glyc3p[c]
+ (0.33) palmACP[c] => (0.01) 12dag3p_PA[c] + ACP[c]
subsystem: blankfield
- id: 13DAMPPOX
name: 1,3-diaminopropane oxidase
equation: o2[c] + h2o[c] + 13dampp[c] => h[c] + nh4[c] + h2o2[c] + 3ampa[c]
- id: 1HPHEs
name: 1-hydroxyphenazine synthase
genes: PA4217
equation: h[c] + o2[c] + nadh[c] + pca[c] => nad[c] + 1hphe[c] + h2o[c] + co2[c]
subsystem: blankfield
- id: 1PYRRD
name: 1-pyrroline dehydrogenase
genes: PA5373
equation: nad[c] + (2) h2o[c] + 1pyrr[c] => h[c] + nadh[c] + 4abut[c]
subsystem: blankfield
- id: 24DAB4AT
name: L-2,4-diaminobutyrate:2-ketoglutarate 4-aminotransferase, PvdH
genes: PA2413
equation: 24dab[c] + akg[c] <=> aspsa[c] + glu__L[c]
subsystem: blankfield
- id: 25DOPs
name: delta-aminovalerate aminotransferase
equation: damval[c] + akg[c] => (2) h[c] + glusa[c] + glu__L[c]
- id: 2AEPPNAT
name: 2-aminoethylphosphonate:pyruvate aminotransferase
genes: PA1310
equation: pyr[c] + 2aeppn[c] <=> ppaca[c] + ala__L[c]
subsystem: blankfield
- id: 2DGLCNDH
name: 2-deoxy-D-gluconate 3-dehydrogenase
genes: PA2892 or PA4098 or PA4079 or PA3387
equation: 2dglcn[c] + nad[c] => nadh[c] + 3ddgc[c] + h[c]
subsystem: blankfield
- id: 2DGLCNRy2i
name: 2-dehydro-D-gluconate reductase extracellular (NADPH) (irreversible)
genes: PA2264 and PA2265
equation: glcn__D[e] + nadp[c] => h[c] + 2dhglcn[e] + nadph[c]
subsystem: blankfield
- id: 2DHGLCNti
name: 2-dehydro-D-gluconate transport (irreversible)
genes: PA2262
equation: 2dhglcn[e] => 2dhglcn[c]
subsystem: blankfield
- id: 2HDDACPs
name: S-2-hydroxylauroyl-ACP synthase
genes: PA4512 or PA0936
equation: (0.5) o2[c] + ddcaACP[c] => 2hddACP[c]
subsystem: blankfield
- id: 2HMYRSACPs
name: S-2-hydroxymyristoyl-ACP synthase
genes: PA4512 or PA0936
equation: (0.5) o2[c] + myrsACP[c] => 2hmyrsACP[c]
subsystem: blankfield
- id: 2MBDT
name: S-(2-Methylbutanoyl)-dihydrolipoamide
genes: PA1586
equation: coa[c] + 2mbutdhla[c] => dhlam[c] + 2mbcoa[c]
subsystem: blankfield
- id: 2NPDO
name: 2-Nitropropane Dioxygenase
genes: PA1024
equation: o2[c] + (2) n2ppn[c] <=> (2) acetone[c] + (2) no2[c] + (2) h[c]
subsystem: blankfield
- id: 3ABUTabc
name: 4-Aminobutyrate transport via ABC system
genes: PA1074 and PA1073 and PA1072 and PA1071 and PA1070
equation: 4abut[e] + atp[c] + h2o[c] => pi[c] + h[c] + 4abut[c] + adp[c]
subsystem: Transport Extracellular
- id: 3AMPADH
name: 3-aminopropanaldehyde dehydrogenase
genes: PA5312
equation: nad[c] + h2o[c] + 3ampa[c] => h[c] + nadh[c] + ala__B[c]
subsystem: blankfield
- id: 3DMUBQ9MT
name: 3-demethylubiquinone-9 3-methyltransferase
genes: PA3171
equation: 3dmubq9[c] + amet[c] <=> ubq9[c] + h[c] + ahcys[c]
subsystem: blankfield
- id: 3H3H
name: unknown enzyme
equation: h2o[c] + 2bhdccoa[c] => 3h3h[c] + coa[c]
- id: 3HBUTDH
name: 3-hydroxybutyrate dehydrogenase
genes: PA2003
equation: nad[c] + 3hbut__R[c] <=> nadh[c] + acac[c] + h[c]
subsystem: blankfield
- id: 3MBT
name: S-(3-Methylbutanoyl)-dihydrolipoamide
genes: PA1586
equation: 3mbutdhla[c] + coa[c] => ivcoa[c] + dhlam[c]
subsystem: Leucine degradation
- id: 3OCHLA
name: 3-oxo-C12-homoserine lactone acylase
genes: PA2385
equation: h2o[c] + n3oxdd__hsl[c] => 3oxdd[c] + hsl[c] + h[c]
subsystem: blankfield
- id: 3OXACOA
name: 3-oxoadipyl-CoA thiolase
genes: PA0228
equation: coa[c] + oxadpcoa[c] => accoa[c] + succoa[c]
subsystem: blankfield
- id: 4ABUTNC
name: 4-aminobutanoate cyclization reaction
equation: 4abutn[c] => 1pyrr[c] + h2o[c] + h[c]
- id: 4AHD
name: 4a-hydroxytetrahydrobiopterin dehydratase;
genes: PA0871
equation: 5678thh[c] <=> 78dhp[c] + h2o[c]
subsystem: blankfield
- id: 4AHD2
name: 4a-hydroxytetrahydrobiopterin dehydratase;
genes: PA0871
equation: 4hthb[c] <=> h2o[c] + dhbpt[c]
subsystem: blankfield
- id: 4HBZt
name: 4-Hydroxybenzoate transport
genes: PA0235
equation: 4hbz[e] + h[e] <=> 4hbz[c] + h[c]
subsystem: blankfield
- id: 4HPHAC3MO
name: 4-hydroxyphenylacetate 3-monooxygenase
genes: PA4091 and PA4092
equation: h[c] + 4hphac[c] + o2[c] + nadh[c] <=> nad[c] + h2o[c] + 34dhpha[c]
subsystem: blankfield
- id: 4HTHRS
name: 4-Hydroxy-L-threonine synthase
genes: PA3735
equation: phthr[c] + h2o[c] => 4hthr[c] + pi[c]
subsystem: Pyridoxine Metabolism
- id: 5CM2HMSDH
name: 5-carboxy-2-hydroxymuconate semialdehyde dehydrogenase
genes: PA4123
equation: nad[c] + h2o[c] + 5cm2hms[c] <=> h[c] + nadh[c] + 5cm2hm[c]
subsystem: blankfield
- id: 5MPCAs
name: probable phenazine-specific methyltransferase
genes: PA4209
equation: pca[c] + amet[c] => ahcys[c] + 5mpca[c]
subsystem: blankfield
- id: 5MTAti
name: 5mta transport irreversible, extracellular
equation: 5mta[c] => 5mta[e]
- id: A5PISO
name: arabinose-5-phosphate isomerase
genes: PA4457
equation: ru5p__D[c] <=> ara5p[c]
subsystem: Alternate Carbon Metabolism
- id: ABTA
name: 4-aminobutyrate transaminase
genes: PA0266
equation: 4abut[c] + akg[c] => glu__L[c] + sucsal[c]
subsystem: Amino Acid Degradation
- id: ABTNabc
name: Aerobactin transport via ABC system
genes: PA2912
equation: abtn[e] + atp[c] + h2o[c] => pi[c] + h[c] + abtn[c] + adp[c]
subsystem: blankfield
- id: ABUTD
name: aminobutyraldehyde dehydrogenase
genes: PA0219 or PA5312
equation: nad[c] + h2o[c] + 4abutn[c] => (2) h[c] + nadh[c] + 4abut[c]
subsystem: Amino Acid Degradation
- id: ACAC
name: acetoacetyl-CoAsynthetase
genes: PA1997
equation: atp[c] + coa[c] + acac[c] => aacoa[c] + ppi[c] + amp[c]
subsystem: blankfield
- id: ACACT1
name: acetyl-CoA C-acetyltransferase
genes: PA2001
equation: (2) accoa[c] => aacoa[c] + coa[c]
subsystem: Leucine degradation
- id: ACACT10rr
name: acetyl-CoA C-acyltransferase (2-Methyl-3-acetoacetyl-CoA)
genes: PA1736
equation: 2maacoa[c] + coa[c] <=> ppcoa[c] + accoa[c]
subsystem: blankfield
- id: ACACT1r
name: acetyl-CoA C-acetyltransferase
genes: PA2001
equation: (2) accoa[c] <=> aacoa[c] + coa[c]
subsystem: Fatty Acid Metabolism
- id: ACCOACr
name: acetyl-CoA carboxylase
genes: PA3639 and PA4847 and PA4848 and PA3112
equation: accoa[c] + hco3[c] + atp[c] <=> pi[c] + h[c] + malcoa[c] + adp[c]
subsystem: blankfield
- id: ACGK
name: acetylglutamate kinase
genes: PA5323
equation: acglu[c] + atp[c] => acg5p[c] + adp[c]
subsystem: Arginine Putriscine and Spermidine Metabolism
- id: ACGS
name: N-acetylglutamate synthase
genes: PA5204
equation: accoa[c] + glu__L[c] => h[c] + acglu[c] + coa[c]
subsystem: Arginine Putriscine and Spermidine Metabolism
- id: ACHBS
name: 2-aceto-2-hydroxybutanoate synthase
genes: PA4695 and PA4696
equation: h[c] + 2obut[c] + pyr[c] => 2ahbut[c] + co2[c]
subsystem: Branched Chain Amino Acid Biosynthesis
- id: ACKr
name: acetate kinase
genes: PA0836 or PA3751
equation: atp[c] + ac[c] <=> adp[c] + actp[c]
subsystem: Pyruvate metabolism
- id: ACLS
name: acetolactate synthase (Also catalyzes ACHBS)
genes: PA4695 and PA4696
equation: (2) pyr[c] + h[c] => alac__S[c] + co2[c]
subsystem: Branched Chain Amino Acid Biosynthesis
- id: ACMAT1
name: Acyl-[acyl-carrier-protein]:malonyl-[acyl-carrier-protein] C-acyltransferase
(decarboxylating)
genes: PA5174 or PA2965 or PA1609
equation: malACP[c] + acACP[c] + h[c] => actACP[c] + co2[c] + ACP[c]
subsystem: blankfield
- id: ACOAD1
name: acyl-CoA dehydrogenase (butanoyl-CoA)
equation: nadh[c] + butd2coa[c] + h[c] <=> btcoa[c] + nad[c]
- id: ACOAD10
name: Acyl-CoA dehydrogenase (2-Methylbutanoyl - trans-2-methylbut)
genes: PA0879
equation: 2mbcoa[c] + fad[c] <=> fadh2[c] + 2mb2coa[c]
subsystem: blankfield
- id: ACOAD20
name: acyl-CoA dehydrogenase (2-methylbutnoyl-CoA)
genes: PA5020
equation: (2) 2mbcoa[c] + o2[c] => (2) 2mb2coa[c] + (2) h2o[c]
subsystem: blankfield
- id: ACOAD8
name: isovaleryl-coA dehydrogenase
genes: PA2015
equation: ivcoa[c] + fad[c] => 3mb2coa[c] + fadh2[c]
subsystem: blankfield
- id: ACODA
name: acetylornithine deacetylase
genes: PA5206
equation: acorn[c] + h2o[c] => orn__L[c] + ac[c]
subsystem: Arginine Putriscine and Spermidine Metabolism
- id: ACONT
name: aconitase
genes: PA1787 or PA1562
equation: cit[c] <=> icit[c]
subsystem: Citrate Cycle (TCA)
- id: ACOTA
name: acetylornithine transaminase
genes: PA0895
equation: acorn[c] + akg[c] <=> glu__L[c] + acg5sa[c]
subsystem: Arginine Putriscine and Spermidine Metabolism
- id: ACPS1
name: acyl-carrier protein synthase
genes: PA1165
equation: coa[c] + apoACP[c] => ACP[c] + h[c] + pap[c]
subsystem: Coenzyme A Biosynthesis
- id: ACS
name: acetyl-CoA synthetase
genes: PA2555 or PA4733 or PA0887
equation: ac[c] + atp[c] + coa[c] => accoa[c] + ppi[c] + amp[c]
subsystem: blankfield
- id: ACt6
name: acetate transport in/out via proton symport
equation: ac[e] + h[e] <=> ac[c] + h[c]
- id: ADA
name: Adenosine deaminase
genes: PA0148
equation: h2o[c] + adn[c] + h[c] => ins[c] + nh4[c]
subsystem: Salvage Pathways
- id: ADCL
name: 4-aminobenzoate synthase
genes: PA2964
equation: 4adcho[c] => 4abz[c] + h[c] + pyr[c]
subsystem: Folate Metabolism
- id: ADCOBASr
name: adenosylcobinamide-phosphate synthase
genes: PA1276 or PA1275
equation: 1ap2ol[c] + adcobhex[c] <=> adcoba[c] + h2o[c]
subsystem: blankfield
- id: ADCOBHEXS
name: adenosylcobyric acid synthase
genes: PA1277
equation: (4) gln__L[c] + (4) atp[c] + (4) h2o[c] + adcobdam[c] => (4) glu__L[c]
+ (4) h[c] + (4) pi[c] + (4) adp[c] + adcobhex[c]
subsystem: blankfield
- id: ADCS
name: 4-amino-4-deoxychorismate synthase
genes: PA1758
equation: gln__L[c] + chor[c] => 4adcho[c] + glu__L[c]
subsystem: Folate Metabolism
- id: ADD
name: adenine deaminase
genes: PA0148
equation: h2o[c] + ade[c] + h[c] => nh4[c] + hxan[c]
subsystem: blankfield
- id: ADICs
name: phenazine-1-carboxylic acid synthesis, step 1
genes: PA4214 or PA1903
equation: chor[c] + gln__L[c] => glu__L[c] + a4dic[c]
subsystem: blankfield
- id: ADK1
name: adenylate kinase
genes: PA3686
equation: atp[c] + amp[c] <=> (2) adp[c]
subsystem: Salvage Pathways
- id: ADK3
name: guanylate kinase (aMP:gTP)
genes: PA3686
equation: gtp[c] + amp[c] <=> gdp[c] + adp[c]
subsystem: Salvage Pathways
- id: ADK4
name: adentylate kinase (ITP)
genes: PA3686
equation: itp[c] + amp[c] <=> idp[c] + adp[c]
subsystem: Salvage Pathways
- id: ADMDC
name: Adenosylmethionine decarboxylase
genes: PA0654
equation: amet[c] + h[c] <=> ametam[c] + co2[c]
subsystem: Arginine Putriscine and Spermidine Metabolism
- id: ADNCYC
name: adenylate cyclase
genes: PA2191 or PA5272 or PA3217
equation: atp[c] => ppi[c] + camp[c]
subsystem: blankfield
- id: ADNK1
name: adenosine kinase
genes: PA1950
equation: atp[c] + adn[c] => amp[c] + h[c] + adp[c]
subsystem: Salvage Pathways
- id: ADPT
name: adenine phosphoribosyltransferase
genes: PA1543
equation: prpp[c] + ade[c] => ppi[c] + amp[c]
subsystem: Salvage Pathways
- id: ADSK
name: adenylyl-sulfate kinase
genes: PA1393
equation: atp[c] + aps[c] => h[c] + paps[c] + adp[c]
subsystem: Cysteine Metabolism
- id: ADSL1r
name: adenylsuccinate lyase
genes: PA3517 or PA3516 or PA2629
equation: dcamp[c] <=> fum[c] + amp[c]
subsystem: Purine and Pyrimidine Biosynthesis
- id: ADSL2r
name: adenylosuccinate lyase
genes: PA2629
equation: 25aics[c] <=> fum[c] + aicar[c]
subsystem: Purine and Pyrimidine Biosynthesis
- id: ADSS_i
name: adenylosuccinate synthetase
genes: PA4938
equation: imp[c] + gtp[c] + asp__L[c] => pi[c] + (2) h[c] + dcamp[c] + gdp[c]
subsystem: Purine and Pyrimidine Biosynthesis
- id: AGDC
name: N-acetylglucosamine-6-phosphate deacetylase
genes: PA3758
equation: acgam6p[c] + h2o[c] => ac[c] + gam6p[c]
subsystem: Alternate Carbon Metabolism
- id: AGMHE
name: ADP-D-glycero-D-manno-heptose epimerase
genes: PA3337
equation: adphep__D,D[c] => adphep__L,D[c]
subsystem: Cell Envelope Biosynthesis
- id: AGMT
name: agmatinase
genes: PA0288 or PA1421
equation: agm[c] + h2o[c] => urea[c] + ptrc[c]
subsystem: Arginine Putriscine and Spermidine Metabolism
- id: AGMTNDMN
name: agmatine deiminase
genes: PA0292
equation: agm[c] + h2o[c] => nh3[c] + cbmps[c] + h[c]
subsystem: blankfield
- id: AGPR
name: N-acetyl-g-glutamyl-phosphate reductase
genes: PA0662
equation: pi[c] + nadp[c] + acg5sa[c] <=> nadph[c] + acg5p[c] + h[c]
subsystem: Arginine Putriscine and Spermidine Metabolism
- id: AHAI
name: acetohydroxy acid isomeroreductase
genes: PA4694
equation: alac__S[c] + nadph[c] + h[c] => nadp[c] + 23dhmb[c]
subsystem: Branched Chain Amino Acid Biosynthesis
- id: AHC
name: adenosylhomocysteinase
genes: PA0432
equation: ahcys[c] + h2o[c] <=> hcys__L[c] + adn[c]
subsystem: Methionine Metabolism
- id: AHMMPS
name: 4-amino-5-hydroxymethyl-2-methylpyrimidine synthetase
genes: PA4973
equation: air[c] + h2o[c] => pi[c] + (0.5) o2[c] + 4ahmmp[c] + gcald[c]
subsystem: Thiamine Metabolism
- id: AHSERL
name: O-acetylhomoserine (thiol)-lyase
genes: PA5025
equation: achms[c] + ch4s[c] => h[c] + ac[c] + met__L[c]
subsystem: blankfield
- id: AICART
name: phosphoribosylaminoimidazolecarboxamide formyltransferase
genes: PA4854
equation: 10fthf[c] + aicar[c] <=> thf[c] + fprica[c]
subsystem: Purine and Pyrimidine Biosynthesis
- id: AIRC1
name: phosphoribosylaminoimidazole carboxylase (ATP-dependent)
genes: PA5425
equation: co2[c] + h2o[c] + air[c] + atp[c] => pi[c] + adp[c] + 5aizc[c] + (2)
h[c]
subsystem: Purine and Pyrimidine Biosynthesis
- id: AIRC3
name: phosphoribosylaminoimidazole carboxylase (mutase rxn)
genes: PA5426
equation: 5aizc[c] <=> 5caiz[c]
subsystem: Purine and Pyrimidine Biosynthesis
- id: AIRCr
name: phosphoribosylaminoimidazole carboxylase
genes: PA5425 or PA5426
equation: air[c] + co2[c] <=> 5aizc[c] + h[c]
subsystem: blankfield
- id: AKGD
name: 2-oxoglutarate dehydrogenase
genes: PA4829 and PA1585 and PA1586
equation: nad[c] + coa[c] + akg[c] => co2[c] + succoa[c] + nadh[c]
subsystem: Citrate Cycle (TCA)
- id: AKGt2
name: 2-oxoglutarate transport in via proton symport
genes: PA0229
equation: akg[e] + h[e] => akg[c] + h[c]
subsystem: blankfield
- id: AKGt6
name: 2-oxoglutarate transport in/out via proton symport
genes: PA5530
equation: akg[e] + h[e] <=> akg[c] + h[c]
subsystem: Transport Extracellular
- id: AKP1
name: alkaline phosphatase (Dihydroneopterin)
genes: PA3296
equation: (3) h2o[c] + ahdt[c] => (2) h[c] + (3) pi[c] + dhnpt[c]
subsystem: Folate Metabolism
- id: ALAALA
name: D-alanine-D-alanine ligase (reversible)
genes: PA4201 and PA4410
equation: atp[c] + (2) ala__D[c] <=> pi[c] + h[c] + alaala[c] + adp[c]
subsystem: Cell Envelope Biosynthesis
- id: ALAR
name: alanine racemase
genes: PA4930
equation: ala__L[c] <=> ala__D[c]
subsystem: Alanine Biosynthesis
- id: ALARi
name: alanine racemase (irreversible)
genes: PA5302
equation: ala__L[c] => ala__D[c]
subsystem: Alanine Biosynthesis
- id: ALATA_G2
name: Glutamine transaminase
genes: PA2444 or PA5415
equation: glu__L[c] + pydx5p[c] => akg[c] + pyam5p[c]
subsystem: Pyridoxine Metabolism
- id: ALATA_L
name: L-alanine transaminase
genes: PA2828
equation: akg[c] + ala__L[c] <=> glu__L[c] + pyr[c]
subsystem: Alanine Biosynthesis
- id: ALATA_L2
name: alanine transaminase
genes: PA5415 or PA2444 or PA4602
equation: pydx5p[c] + ala__L[c] => pyr[c] + pyam5p[c]
subsystem: Pyridoxine Metabolism
- id: ALATRS
name: Alanyl-tRNA synthetase
genes: PA0903
equation: trnaala[c] + ala__L[c] + atp[c] <=> alatrna[c] + ppi[c] + amp[c]
subsystem: blankfield
- id: ALA_Dt6
name: D-alanine transport in/out via proton symport
genes: PA0789
equation: ala__D[e] + h[e] <=> ala__D[c] + h[c]
subsystem: Transport Extracellular
- id: ALAabc
name: L-alanine transport via ABC system
genes: PA1074 and PA1073 and PA1072 and PA1071 and PA1070
equation: ala__L[e] + atp[c] + h2o[c] => pi[c] + h[c] + ala__L[c] + adp[c]
subsystem: Transport Extracellular
- id: ALAt7
name: probable AGCS sodium/alanine/glycine symporter
genes: PA3461 or PA2252 or PA2533
equation: na1[e] + ala__L[e] <=> na1[c] + ala__L[c]
subsystem: blankfield
- id: ALCD19
name: alcohol dehydrogenase (glycerol)
genes: PA3629
equation: nadh[c] + glyald[c] + h[c] <=> nad[c] + glyc[c]
subsystem: Alternate Carbon Metabolism
- id: ALCDUBQ8
name: alcohol dehydrogenase (ethanol, ubq8)
genes: PA5427 or (PA1982 and PA1983)
equation: etoh[c] + ubq8[c] <=> ubq8h2[c] + acald[c]
subsystem: blankfield
- id: ALDD1x
name: aldehyde dehydrogenase (formaldehyde, NAD)
genes: PA5421
equation: fald[c] + nad[c] + h2o[c] => (2) h[c] + nadh[c] + for[c]
subsystem: blankfield
- id: ALDD2x
name: aldehyde dehydrogenase (acetaldehyde, NAD)
genes: PA1984 or PA4022 or PA0219 or PA5312
equation: nad[c] + h2o[c] + acald[c] => (2) h[c] + ac[c] + nadh[c]
subsystem: Alternate Carbon Metabolism
- id: ALGD
name: GDP-mannose 6-dehydrogenase
genes: PA3540
equation: (2) nad[c] + gdpman[c] + h2o[c] <=> (3) h[c] + (2) nadh[c] + gdpmanur[c]
subsystem: blankfield
- id: ALGE
name: Alginate production outer membrane protein
genes: PA3544
equation: algna[c] => algna[e]
subsystem: blankfield
- id: ALGLi
name: Poly(beta-d-mannuronate) lyase precursor
genes: PA3542 and PA3541
equation: (2) gdpmanur[c] => (2) gdp[c] + algn[c]
subsystem: blankfield
- id: ALGNA
name: alginate o-acetyltransferase
genes: PA3550 and PA3548 and PA3549
equation: algne[c] + acACP[c] => ACP[c] + algna[c]
subsystem: blankfield
- id: ALGNE
name: alginate-c5-mannuronan-epimerase
genes: PA3545 and PA3543 and PA3546
equation: algn[c] => algne[c]
subsystem: blankfield
- id: ALLTAH
name: allantoicase
genes: PA1515
equation: alltt[c] + h2o[c] => urea[c] + urdglyc[c]
subsystem: blankfield
- id: ALLTN
name: allantoinase
equation: h2o[c] + alltn[c] => alltt[c] + h[c]
- id: ALLTNt6
name: allantoin transport in/out via proton symport
genes: PA0443 or PA1419 or PA2073 or PA0438 or PA0476 or PA5099
equation: alltn[e] + h[e] <=> alltn[c] + h[c]
subsystem: blankfield
- id: AMAA
name: N-acetylmuramoyl-L-alanine amidase
genes: PA4947
equation: h2o[c] + acmama[c] => acmam[c] + ala__L[c]
subsystem: blankfield
- id: AMAOT
name: adenosylmethionine-8-amino-7-oxononanoate transaminase
genes: PA0420
equation: 8aonn[c] + amet[c] <=> dann[c] + amob[c]
subsystem: Biotin Biosynthesis
- id: AMMQT8_2
name: S-adenosylmethione:2-demethylmenaquinone methyltransferase
genes: PA1772
equation: 2dmmq8[c] + amet[c] => mqn8[c] + h[c] + ahcys[c]
subsystem: Quinone Biosynthesis Menaquinone
- id: AMPN
name: AMP nucleosidase
genes: PA3970
equation: h2o[c] + amp[c] => ade[c] + r5p[c]
subsystem: Salvage Pathways
- id: ANO2i
name: assimilatory nitrite reductase
genes: PA1781 and PA1780
equation: (4) h[c] + (3) nadh[c] + no2[c] => (3) nad[c] + h2o[c] + nh4oh[c]
subsystem: blankfield
- id: ANPRT
name: anthranilate phosphoribosyltransferase
genes: PA0650
equation: prpp[c] + anth[c] => ppi[c] + pran[c]
subsystem: Aromatic Amino Acids
- id: ANS1
name: anthranilate synthase
genes: (PA1001 and PA1002) or (PA0609 and PA0649)
equation: chor[c] + gln__L[c] => h[c] + glu__L[c] + pyr[c] + anth[c]
subsystem: Aromatic Amino Acids
- id: AOXS
name: 8-amino-7-oxononanoate synthase
genes: PA0501
equation: h[c] + pmcoa[c] + ala__L[c] <=> 8aonn[c] + coa[c] + co2[c]
subsystem: Biotin Biosynthesis
- id: AP4AHr
name: Ap4A hydrolase, reversible
genes: PA0590
equation: h2o[c] + ap4a[c] <=> (2) h[c] + (2) adp[c]
subsystem: blankfield
- id: APRAUR
name: 5-amino-6-(5-phosphoribosylamino)uracil reductase
genes: PA4056
equation: 5apru[c] + nadph[c] + h[c] => nadp[c] + 5aprbu[c]
subsystem: Riboflavin Metabolism
- id: ARGAGMt
name: Arginine:Agmatine antiporter
genes: PA1819
equation: agm[c] + arg__L[e] <=> arg__L[c] + agm[e]
subsystem: blankfield
- id: ARGDC
name: arginine decarboxylase
genes: PA4839 or PA4519 or PA1818
equation: h[c] + arg__L[c] => agm[c] + co2[c]
subsystem: Arginine Putriscine and Spermidine Metabolism
- id: ARGDE
name: arginine deiminase
genes: PA5171
equation: h2o[c] + arg__L[c] <=> h[c] + nh3[c] + citr__L[c]
subsystem: blankfield
- id: ARGN
name: arginase
genes: PA1421 or PA0288 or PA3175
equation: arg__L[c] + h2o[c] => orn__L[c] + urea[c]
subsystem: Amino Acid Degradation
- id: ARGORNt3
name: Arginine/ornithine antiporter
genes: PA5170
equation: orn__L[c] + arg__L[e] <=> orn__L[e] + arg__L[c]
subsystem: blankfield
- id: ARGSL
name: argininosuccinate lyase
genes: PA5263
equation: argsuc[c] <=> fum[c] + arg__L[c]
subsystem: Arginine Putriscine and Spermidine Metabolism
- id: ARGSS
name: argininosuccinate synthase
genes: PA3525
equation: citr__L[c] + atp[c] + asp__L[c] => h[c] + argsuc[c] + ppi[c] + amp[c]
subsystem: Arginine Putriscine and Spermidine Metabolism
- id: ARGTRS
name: Arginyl-tRNA synthetase
genes: PA5051
equation: arg__L[c] + trnaarg[c] + atp[c] => argtrna[c] + ppi[c] + amp[c]
subsystem: blankfield
- id: ARGabc
name: L-arginine transport via ABC system
genes: (PA0888 and PA0890 and PA0892 and PA0889) or (PA1256 and PA1257 and PA1258
and PA1260) or (PA5152 and PA5153 and PA5154 and PA5155)
equation: arg__L[e] + atp[c] + h2o[c] => pi[c] + arg__L[c] + h[c] + adp[c]
subsystem: Transport Extracellular
- id: ARSNR
name: arsenate reductase
genes: PA0950
equation: arsna[c] + gtd[c] <=> gtdss[c] + arsni[c]
subsystem: blankfield
- id: ASAD
name: aspartate-semialdehyde dehydrogenase
genes: PA3116 or PA3117
equation: pi[c] + nadp[c] + aspsa[c] <=> h[c] + 4pasp[c] + nadph[c]
subsystem: Threonine and Lysine Metabolism
- id: ASCt2
name: ascorbate transport in via proton symport
genes: PA2073 or PA0166 or PA2938 or PA0476 or PA5099 or PA0352 or PA0438 or PA0443
or PA1419 or PA4647 or PA1507
equation: ascb[e] + h[e] => ascb[c] + h[c]
subsystem: blankfield
- id: ASNN
name: L-asparaginase
genes: PA2253 or PA1337
equation: h2o[c] + asn__L[c] => nh4[c] + asp__L[c]
subsystem: Amino Acid Degradation
- id: ASNS1
name: asparagine synthase (glutamine-hydrolysing)
genes: PA0051 or PA3459 or PA2084
equation: gln__L[c] + atp[c] + asp__L[c] + h2o[c] => glu__L[c] + h[c] + asn__L[c]
+ ppi[c] + amp[c]
subsystem: Asparagine metabolism
- id: ASNabc
name: L-asparagine transport via ABC system
genes: PA3858
equation: asn__L[e] + atp[c] + h2o[c] => pi[c] + h[c] + asn__L[c] + adp[c]
subsystem: blankfield
- id: ASP1DC
name: aspartate 1-decarboxylase
genes: PA4731
equation: h[c] + asp__L[c] => co2[c] + ala__B[c]
subsystem: Coenzyme A Biosynthesis
- id: ASPCT
name: aspartate carbamoyltransferase
genes: PA0402
equation: asp__L[c] + cbp[c] => cbasp[c] + h[c] + pi[c]
subsystem: Purine and Pyrimidine Biosynthesis
- id: ASPK
name: aspartate kinase
genes: PA0904
equation: asp__L[c] + atp[c] <=> 4pasp[c] + adp[c]
subsystem: Threonine and Lysine Metabolism
- id: ASPO6
name: L-aspartate oxidase
genes: PA0761
equation: asp__L[c] + o2[c] => h2o2[c] + iasp[c] + h[c]
subsystem: NAD Biosynthesis
- id: ASPO8
name: L-aspartate oxidase
genes: PA1004 and PA0761
equation: asp__L[c] + dhap[c] + fad[c] => pi[c] + h[c] + quln[c] + (2) h2o[c] +
fadh2[c]
subsystem: blankfield
- id: ASPT
name: L-aspartase
genes: PA5429
equation: asp__L[c] => fum[c] + nh4[c]
subsystem: Amino Acid Degradation
- id: ASPTA1
name: aspartate transaminase
genes: PA4976
equation: akg[c] + asp__L[c] <=> glu__L[c] + oaa[c]
subsystem: Asparagine metabolism
- id: ASPTRS
name: Aspartyl-tRNA synthetase
genes: PA0963
equation: atp[c] + trnaasp[c] + asp__L[c] => asptrna[c] + ppi[c] + amp[c]
subsystem: blankfield
- id: ASPabc
name: L-aspartate transport via ABC system
genes: (PA1256 and PA1257 and PA1258 and PA1260) or (PA4192 and PA4194 and PA4195)
or (PA1339 and PA1340 and PA1341 and PA1342)
equation: asp__L[e] + atp[c] + h2o[c] => asp__L[c] + pi[c] + h[c] + adp[c]
subsystem: Transport Extracellular
- id: ASPt6
name: L-aspartate transport in via proton symport
genes: PA5479
equation: asp__L[e] + h[e] <=> asp__L[c] + h[c]
subsystem: Transport Extracellular
- id: ATPM
name: ATP maintenance requirment
equation: atp[c] + h2o[c] => adp[c] + pi[c] + h[c]
- id: ATPPRT
name: ATP phosphoribosyltransferase
genes: PA4449
equation: atp[c] + prpp[c] => prbatp[c] + ppi[c]
subsystem: Histidine Metabolism
- id: ATPS4r
name: ATP synthase (four protons for one ATP)
genes: PA1104 or PA1697 or (PA5556 and PA5560 and PA5553 and PA5554 and PA5559
and PA5558 and PA5555 and PA5557 and PA5561)
equation: pi[c] + (4) h[e] + adp[c] <=> (3) h[c] + atp[c] + h2o[c]
subsystem: Oxidative phosphorylation
- id: BADH
name: betaine-aldehyde dehydrogenase
genes: PA4073 or PA5312 or PA1027 or PA3504 or PA4189 or PA5373 or PA0219 or PA1984
or PA4022 or PA4899 or PA2125
equation: betald[c] + nad[c] + h2o[c] => glyb[c] + nadh[c] + (2) h[c]
subsystem: blankfield
- id: BALAAT
name: beta-alanine--pyruvate transaminase
genes: PA0132
equation: msa[c] + ala__L[c] <=> ala__B[c] + pyr[c]
subsystem: blankfield
- id: BENA
name: Benzoate dioxygenase (complex)
genes: PA2518 and PA2517 and PA2516
equation: (2) h[c] + nadh[c] + bz[c] + o2[c] => nad[c] + bencisdiol[c]
subsystem: blankfield
- id: BENZ
name: benzoylformate decarboxylase
genes: PA4901
equation: benz[c] <=> bzal[c] + co2[c]
subsystem: blankfield
- id: BLACT
name: beta-lactamase
genes: PA4110
equation: pencil[c] + h2o[c] <=> pencilca[c] + h[c]
subsystem: blankfield
- id: BPNT
name: 3',5'-bisphosphate nucleotidase
genes: PA5175
equation: pap[c] + h2o[c] => amp[c] + pi[c]
subsystem: Cysteine Metabolism
- id: BTDD__RR
name: (R,R)-butanediol dehydrogenase
genes: PA4153
equation: nad[c] + btd__RR[c] <=> nadh[c] + actn__R[c] + h[c]
subsystem: blankfield
- id: BTDt6__RR
name: Butanediol transport in/out via proton symport
equation: btd__RR[e] + h[e] <=> btd__RR[c] + h[c]
- id: BTMAT1
name: Butyryl-[acyl-carrier protein]:malonyl-CoA C-acyltransferase
genes: PA1806
equation: nadh[c] + h[c] + 2beACP[c] => nad[c] + butACP[c]
subsystem: blankfield
- id: BTNC
name: Biotin carboxylase
genes: PA4848
equation: hco3[c] + atp[c] + btn_cbxl[c] => btn_co2[c] + h[c] + pi[c] + adp[c]
subsystem: blankfield
- id: BTNL1
name: Biotin:CoA ligase (AMP-forming)
genes: PA4280
equation: atp[c] + h[c] + btn[c] => btamp[c] + ppi[c]
subsystem: blankfield
- id: BTSr
name: biotin synthase
genes: PA0500
equation: dtbt[c] + (2) s[c] <=> h2s[c] + btn[c] + h[c]
subsystem: Biotin Biosynthesis
- id: BUTSabc
name: butanesulfonate transport via ABC system
genes: (PA2295 and PA2294) or (PA2308 and PA2307) or (PA3442 and PA3443)
equation: atp[c] + h2o[c] + buts[e] => pi[c] + buts[c] + h[c] + adp[c]
subsystem: blankfield
- id: C4HLA
name: C4-homoserine lactone acylase
genes: PA2385
equation: h2o[c] + nb__hsl[c] => but[c] + hsl[c] + h[c]
subsystem: blankfield
- id: CAT
name: catalase
genes: PA4236 or PA4613 or PA2147
equation: (2) h2o2[c] => (2) h2o[c] + o2[c]
subsystem: blankfield
- id: CATA
name: Catechol 1,2-dioxygenase
genes: PA2507
equation: catechol[c] + o2[c] => muc[c]
subsystem: blankfield
- id: CATB
name: Muconate cycloisomerase
genes: PA2509
equation: 25d5o2a[c] <=> h[c] + hdd__CC[c]
subsystem: blankfield
- id: CATC
name: Muconolactone delta-isomerase
genes: PA2508
equation: 25d5o2a[c] <=> 5odhf2a[c]
subsystem: blankfield
- id: CBIAT
name: Cobinamide adenyltransferase
genes: PA1272
equation: cbi[c] + atp[c] + h2o[c] <=> pi[c] + adcoba[c] + ppi[c]
subsystem: blankfield
- id: CBMK2
name: Carbamate kinase
genes: PA5173
equation: co2[c] + atp[c] + nh4[c] => adp[c] + cbp[c] + (2) h[c]
subsystem: Arginine Putriscine and Spermidine Metabolism
- id: CBMLPTAH
name: N-carbamoylputrescine amidohydrolase
genes: PA0293
equation: h[c] + h2o[c] + cbmps[c] => nh3[c] + co2[c] + ptrc[c]
subsystem: blankfield
- id: CBPS
name: carbamoyl-phosphate synthase (glutamine-hydrolysing)
genes: PA4758 and PA4756
equation: gln__L[c] + hco3[c] + (2) atp[c] + h2o[c] => glu__L[c] + (2) h[c] + pi[c]
+ (2) adp[c] + cbp[c]
subsystem: Arginine Putriscine and Spermidine Metabolism
- id: CD2t
name: cadmium transport out via antiport
genes: PA2520 and PA2521 and PA2522
equation: cd2[c] + h[e] => h[c] + cd2[e]
subsystem: blankfield
- id: CDGPTr_PA
name: CDPdiacylglycerol:sn-glycerol-3-phosphate 3-phosphatidyltransferase reversible
genes: PA2584
equation: (0.02) cdpdag_PA[c] + glyc3p[c] <=> cmp[c] + h[c] + (0.02) pglyp_PA[c]
subsystem: blankfield
- id: CDPDSPr_PA
name: CDPdiacylglycerol-serine O-phosphatidyltransferase reversible
genes: PA4693
equation: (0.02) cdpdag_PA[c] + ser__L[c] <=> cmp[c] + (0.02) ps_PA[c] + h[c]
subsystem: blankfield
- id: CDPMEK
name: 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase
genes: PA4669
equation: atp[c] + 4c2me[c] => adp[c] + h[c] + 2p4c2me[c]
subsystem: blankfield
- id: CHLabc
name: choline transport via ABC system
genes: ((PA3891 or PA5376) and (PA3890 or PA5377) and (PA5378 or PA3889)) or (PA3891
and PA3890 and PA3889 and PA3888)
equation: chol[e] + atp[c] + h2o[c] => pi[c] + h[c] + chol[c] + adp[c]
subsystem: blankfield
- id: CHLt2
name: choline transport in via proton symport
genes: PA5291 or PA5375 or PA3933
equation: chol[e] + h[e] => chol[c] + h[c]
subsystem: blankfield
- id: CHOLD2
name: choline dehydrogenase (FAD-dependent)
genes: PA5372 or PA0364 or PA3710 or PA4100 or PA2124
equation: chol[c] + fad[c] => betald[c] + fadh2[c]
subsystem: blankfield
- id: CHORM
name: chorismate mutase
genes: PA3166
equation: chor[c] => pphn[c]
subsystem: Aromatic Amino Acids
- id: CHORS
name: chorismate synthase
genes: PA1681
equation: 3psme[c] => pi[c] + chor[c]
subsystem: Aromatic Amino Acids
- id: CHRPL
name: chorismate pyruvate lyase
genes: PA5357
equation: chor[c] => 4hbz[c] + pyr[c]
subsystem: Quinone Biosynthesis Ubiquinone
- id: CITt10
name: citrate transport in via Mg complex
genes: PA5468
equation: cit[e] + mg2[e] + h[e] => h[c] + cit[c] + mg2[c]
subsystem: blankfield
- id: CITt6
name: citrate transport in/out via proton symport
genes: PA5476
equation: h[e] + cit[e] <=> cit[c] + h[c]
subsystem: Transport Extracellular
- id: CLPNS2_PA
name: cardiolipin synthase reversible
genes: PA5394
equation: (0.04) pg_PA[c] <=> (0.02) cdlp_PA[c] + glyc[c]
subsystem: blankfield
- id: CLPNS_PA
name: cardiolipin synthetase
genes: PA2155
equation: (0.02) cdpdag_PA[c] + (0.02) pg_PA[c] => (0.02) cdlp_PA[c] + h[c] + cmp[c]
subsystem: blankfield
- id: CO2t
name: CO2 transport out via diffusion
equation: co2[e] <=> co2[c]
- id: COBALTt
name: cobalt transport out via antiport
genes: PA2520 and PA2521 and PA2522
equation: h[e] + cobalt2[c] => cobalt2[e] + h[c]
subsystem: blankfield
- id: COBALTt5
name: cobalt transport in/out via permease (no H+)
genes: PA5268
equation: cobalt2[c] <=> cobalt2[e]
subsystem: blankfield
- id: COBALTt5i
name: cobalt transport in/out via permease (no H+)
genes: PA0913
equation: cobalt2[e] => cobalt2[c]
subsystem: blankfield
- id: CPPPGO
name: coproporphyrinogen oxidase
genes: PA0024
equation: (2) h[c] + cpppg3[c] + o2[c] => pppg9[c] + (2) h2o[c] + (2) co2[c]
subsystem: Tetrapyrrole Biosynthesis
- id: CPPPGOAN
name: Oxygen Independent coproporphyrinogen-III oxidase
genes: PA1546
equation:
reversible: false
left:
- id: amet
compartment: c
value: 2
- id: nadph
compartment: c
value: 2
- id: fdxo__4_COLON_2
compartment: c
value: 2
- id: cpppg3
compartment: c
value: 1
right:
- id: co2
compartment: c
value: 2
- id: pppg9
compartment: c
value: 1
- id: h
compartment: c
value: 2
- id: met__L
compartment: c
value: 2
- id: dad__5
compartment: c
value: 2
- id: nadp
compartment: c
value: 2
- id: fdxr__4_COLON_2
compartment: c
value: 2
subsystem: blankfield
- id: CRNabc
name: L-carnitine transport via ABC system
genes: ((PA3891 or PA5376) and (PA3890 or PA5377) and (PA5378 or PA3889)) or (PA3891
and PA3890 and PA3889 and PA3888)
equation: crn[e] + atp[c] + h2o[c] => pi[c] + h[c] + crn[c] + adp[c]
subsystem: blankfield
- id: CS
name: citrate synthase