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FastGA is a new pairwise genome aligner that seems like a good candidate to help speed up Cactus.. This PR adds an option to drop it into progressive cactus as a
lastz
replacement.It's got a ways to go before merging though, as it doesn't yet pass the evolver mammals test. Issues so far:
FastGA
aborts when when aligning trimmed ingroups to outgroups. I've hacked around this by disablingtrimIngroups
whenfastga
is activated.Anc0
alignment is empty, leading to acactus_consolidated
crash. I think this is because the ancestor(s) below it are too fragmented forFastGA
to align.Without having spent much time on this, it looks like
FastGA
does not work well with small contigs, at least with its default parameters. This leads to trouble with trimmed and ancestral sequences in Cactus.This branch should still be runnable on pairwise alignments in Cactus, and pairwise tests are probably the next step before seeing how much it's worth pursuing the above issues.