Releases: HKU-BAL/Clair3-RNA
Releases · HKU-BAL/Clair3-RNA
v0.2.1
- Fixed a bug that misses some variants when --print_ref_calls is enabled (#6).
- Added the --enable_variant_calling_at_sequence_head_and_tail option to enable variant calling at the head and tail 16bp of each sequence. Use with caution because alignments are less reliable in the regions, and there would be insufficient context to be fed to the neural network for reliable calling.
v0.2.0
- Added a new pileup phasing model (enable by using --enable_phasing_model option) for ONT dRNA004(ont_dorado_drna004), PacBio Iso-Seq(hifi_sequel2_minimap2), and PacBio MAS-Seq(hifi_mas_minimap2), the SNP performance improved by ~2% and Indel performance improved by ~6%.
- Fixed some formatting issues in the calling workflow.
v0.1.0
- Added a new ONT dRNA004 direct RNA sequencing model (
ont_dorado_drna004
) for SQK-RNA004 kit. - Added new PacBio Sequel (
hifi_sequel2_minimap2
) and Revio (hifi_mas_minimap2
) model to support minimap2 alignment. - Enhance model training techniques to boost performance by incorporating strategies such as managing low-coverage sites, verifying variant zygosity, filtering RNA editing sites, etc.
- Renamed all ONT and PacBio model names, check here for more details.
v0.0.1
Initial release for early access.