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BCR_TCR_Interference

This repository is associated with the publication Single-cell RNA sequencing analyses: interference by the genes that encode the B-cell and T-cell receptors (Sundell et al., 2022).

All R code used to perform the processing and analyses in the manuscript can be found within the repository. The sequencing data for the peripheral memory B cells and bone marrow early B-lineage cells have been submitted and can be found in ArrayExpress, in the form of FASTQ files, under the accession number E-MTAB-12346. The peripheral CD8+ T cell data can be found via the 10x Genomics website. Finally, the relevant VDJ-seq data for the peripheral memory B cell sample can be found in the data/ directory.

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