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Merge pull request #75 from broadinstitute/cleanup
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Cleanup
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shntnu authored Jan 24, 2023
2 parents 6c3e2cc + bb40908 commit e28385d
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7,742 changes: 3,871 additions & 3,871 deletions cmqtl_onErisone_current.r → 3.cmqtl/cmqtl_onErisone_current.r

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# Cell Morphology Quantitative Trait Loci (cmQTL)

Defining the genetic architecture of cell morphology

## Data

We are collecting cell painting data from induced pluripotent stem cells (iPSC) derived from ~1,000 patients.
We also have matched genotype data from these patients.
Our goal is to determine if specific genotypes can be mapped to cell morphology.

## Determining Cell Culture Conditions

Our first step is to determine optimal conditions at which to plate samples in order to generate morphological profiles.
We describe our approach in [0.pilot-determine-conditions](0.pilot-determine-conditions/).

Based on these analyses, we determined that the optimal conditions included plating cells for 6 hours at 10,000 plate density.
High-dimensional phenotyping to define the genetic basis of cellular morphology

## Reproducibility

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