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* read counts must be present in the targets file but the reverse need not be true. | ||
* | ||
* Output is a read counts file with the same targets (rows) and samples (columns) as the input, corrected for GC bias. | ||
* Coverage is represented by doubles in {@link ReadCountCollection}. | ||
* | ||
* @author David Benjamin <[email protected]> | ||
*/ | ||
@CommandLineProgramProperties( | ||
oneLineSummary = "Correct for per-sample GC bias effects.", | ||
summary = "Correct for per-sample GC bias effects.", | ||
summary = "Correct coverage in a read counts files by estimating per-sample bias as a function of target GC" + | ||
" content and dividing input coverage by these derived bias curves.", | ||
programGroup = CopyNumberProgramGroup.class | ||
) | ||
public class CorrectGCBias extends CommandLineProgram { | ||
|