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Draft genome file #184

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ifoo1213 opened this issue Jul 26, 2024 · 0 comments
Open

Draft genome file #184

ifoo1213 opened this issue Jul 26, 2024 · 0 comments

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@ifoo1213
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Hi, thanks for develop this tool to improve the assembly for polyploid plant genome. This is really helpful, just a bit confusing about the draft genome. Normally we use hifiasm to assembly a primary genome which only has half of the genome size, but in this pipeline we aim to assembly all the haplotypes that means the draft genome supposed to contain all double size of the primary assembly right. Because hap1 and hap2 genome assembly from hifiasm is not producing similar genome size. Which draft genome would be preferred to use as a start genome here? A primary assembly? or Combined hap1 and hap2? Thanks

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